Bone Turnover in Preterm Infants

Bone disease in preterm infants.

Metabolic bone disease preterm infants

Small preterm infants often develop osteopenia with or without rickets and with or without fraewres. Whether these Ilone abnormalities all form part of the same disease process with a wide spectrum of presentation or whether each abnormality represents a different disease is as yet unclear. Bone mineralization depends largely on adequate supplies of calcium and phosphate. The normal intra-uteri...

Bone Turnover Markers in Premature Infants

Objective: We aimed to evaluate the bone turnover markers in preterm infants, and analyze their relationship with growth, urinary calcium (Ca) and phosphorus (P). Subjects and Method: Thirty-nine premature infants with enteral feeding started before the 5th day of life, and 20 full-term infants, as control group, were enrolled for the study. The weight and length of all premature infants were m...

Metabolic bone disease in preterm infants.

Small preterm infants often develop osteopenia with or without rickets and with or without fractures. Whether these bone abnormalities all form part of the same disease process with a wide spectrum of presentation or whether each abnormality represents a different disease is as yet unclear. Bone mineralization depends largely on adequate supplies of calcium and phosphate. The normal intra-uteri...

Endogenous surfactant turnover in preterm infants measured with stable isotopes.

We studied surfactant synthesis and turnover in vivo in preterm infants using the stable isotope [U-13C]glucose, as a precursor for the synthesis of palmitic acid in surfactant phosphatidylcholine (PC). Six preterm infants (birth weight, 916 +/- 244 g; gestational age, 27.7 +/- 1.7 wk) received a 24-h [U-13C]glucose infusion on the first day of life. The 13C-enrichment of palmitic acid in surfa...